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• Indole clubbed with thiazolidinone ring represents a novel class of heterocyclic compounds with significant pharmacological potential.
• The indole nucleus is a biologically active scaffold present in many natural and synthetic drugs.
• Thiazolidinone is another important heterocycle known for its wide range of biological activities.
• Combining these two moieties may enhance therapeutic efficacy through synergistic effects.
• These hybrid molecules are being explored for activities like antimicrobial, anti-inflammatory, anticancer, and neuroprotective effects.
• Structural modification of indole-thiazolidinone derivatives allows optimization of pharmacokinetic and pharmacodynamic properties.
• The presence of electron-donating and withdrawing groups influences biological activity significantly.
• Such compounds are synthesized using various organic reactions like cyclization and condensation methods.
• These derivatives are evaluated using in vitro and in vivo experimental models for biological screening.

 

• Overall, indole-thiazolidinone hybrids are promising candidates for the development of new therapeutic agents.

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Qualifications: MASTERS IN PHARMACY (Chemistry)

Work Experience: 6 months

Research Interest: Pharmaceutical chemistry